Specialty Cell Attachment

6+ Unique Surfaces for Preferential Cell Attachment

True cell attachment is very challenging. The scientists at Implant Surfaces control the electrical, chemical and bonding properties of the implant surface to elicit the desired immune response and trigger differentiation into the desired cell type.  Through more than a decade of research combining physics, chemistry, biochemistry and vacuum technology, Implant Surfaces has discovered the proper surface morphologies and charge structures that attract specific cells. Every cell type needs a different surface to maximize cell attachment while minimizing fibroblast encapsulation or inappropriate cell bonding.

While titanium is reasonably biocompatible within the body, and certainly more biocompatible than PEEK and related polymers, the targeted cells for attachment each seek a deeper pattern of surface and charge to preferentially attach. Fibroblasts between bone cells and the implant can lead to potential gaps, infections, and loosening.

We have figured out how to attach osteoblasts to implants with little interference from fibroblasts. Maximize bone on-growth and attachment!

Learn more

IntimateBondᵀᴹ Endothelial

Encourage immediate and complete attachment of cardiovascular endothelial cells to the stent to reduce restenosis. In testing, delivered >4X the restenosis performance target.

IntimateBond™ Periodontal Ligament Fibroblasts

IntimateBond™ Gingival Fibroblasts

Add IntimateBond™ Osteoblast

Yes, each cell type requires a different nanotopology to encourage maximum cell attachment for fixation and healing and to discourage future micro infections and related consequences.

Allowing NO cells to attach to a surface was challenging, requiring a unique specialized surface appropriately named ZERØ.

Learn more

IntimateBond™ Super-Hydrophilic Surface

Super-Hydrophilic Spiky Surface

  • Less than 5º contact angle!
  • Virtually unmeasurable.
  • The surface is superwetting.

Our source “Spiky” surface develops the maximum surface area for drug confinement and elution, sensor sensitivity and improved catalysis from a much smaller footprint.

Learn more