Operating at Nanoscale Where the ”Rules” are Different
Proven in over 50,000 Spine and Foot & Ankle Surgeries
What Does Serious Osteoblast Attachment Look Like? Just Like This.
- Boosts Expulsion Force Required by 74% over Bare PEEK
- Inhibits Fibroblast Encapsulation
- Works on PEEK, Titanium and Titanium Alloy Implants
- Maintains Imaging Properties
- High Adhesion and Impact Resistance
- FDA Master File
Non-line-of-sight, the surface completely coats graft channels, surface channels, pores and complex open geometries to thoroughly integrate the implant with bone.
is nano-engineered to facilitate direct osteoblast attachment to the entire surface of the implant, including graft channels.
nearly eliminates fibroblast encapsulation and maximizes bone tissue growth through and around the implant, significantly reducing complications.
can be applied to various types of spinal, orthopedic, dental and other implants including machined and 3D-printed PEEK, PEKK, titanium and titanium alloy devices with a wide range of geometric configurations, textures and porosity.
The IntimateBond™ surface family includes distinct surfaces for attachment of a range of cell types including Vascular Endothelials, Gingival Fibroblasts and Periodontal Ligament Fibroblasts. It also includes IntimateBond ZERØ Anti-Cell Attachment surfaces to prevent cell attachment.
In an Expulsion Test of IntimateBond coated and uncoated PEEK implants, The coated implants required 74% more force for expulsion.² The IntimateBond coating provided superior expulsion resistance without any further assumptions for rapid osteoblast on-growth to the device in vivo.
1. Reprinted from Spine J_18_(2018)_ Walsh B et al, The in vivo response to a novel Ti coating compared with PEEK- evaluation of the periphery and inner surfaces of an implant, p1237, © 2018, with permission from Elsevier. (Note: NanoMetalene® referenced in paper is SeaSpine’s brand name for IntimateBondTM Osteoblast.)
2. Expulsion testing - The purpose of this test is to determine the mechanical resistance of spinal implants against expulsion loads. Test were conducted using IntimateBond coated PEEK test implants and uncoated PEEK control implants per Accutek protocol VBR-EXPUL-1000. Coated implants showed higher expulsion values (873 N ±42) versus uncoated PEEK (501 N± 15), representing a 74% increase in Ultimate Force (N) required for implant initial expulsion.